Detalhe da pesquisa
1.
Commentary: Why Pharmaceutical Scientists in Early Drug Discovery Are Critical for Influencing the Design and Selection of Optimal Drug Candidates.
AAPS PharmSciTech
; 19(1): 1-10, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28755053
2.
Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase.
Bioorg Med Chem Lett
; 25(22): 5352-6, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26411795
3.
Pharmacokinetics and metabolism studies on the glucagon-like peptide-1 (GLP-1)-derived metabolite GLP-1(9-36)amide in male Beagle dogs.
Xenobiotica
; 44(9): 842-8, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24588343
4.
A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor.
J Med Chem
; 65(12): 8208-8226, 2022 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35647711
5.
Recent trends in product development and regulatory issues on impurities in active pharmaceutical ingredient (API) and drug products. Part 2: Safety considerations of impurities in pharmaceutical products and surveying the impurity landscape.
AAPS PharmSciTech
; 15(1): 237-51, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24363207
6.
Recent trends in product development and regulatory issues on impurities in active pharmaceutical ingredient (API) and drug products. Part 1: Predicting degradation related impurities and impurity considerations for pharmaceutical dosage forms.
AAPS PharmSciTech
; 15(1): 198-212, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24281749
7.
The use of mixed-mode ion-exchange solid phase extraction to characterize pharmaceutical drug degradation.
J Pharm Biomed Anal
; 44(5): 1029-39, 2007 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-17553650
8.
Physicochemical property trends of marketed prodrugs.
Ther Deliv
; 4(2): 225-37, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23343161
9.
Nasal-to-CNS drug delivery: where are we now and where are we heading? An industrial perspective.
Ther Deliv
; 3(2): 195-208, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22834197
10.
Discovery of 1-[9-(4-chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic acid amide hydrochloride (CP-945,598), a novel, potent, and selective cannabinoid type 1 receptor antagonist.
J Med Chem
; 52(2): 234-7, 2009 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19102698
11.
Stabilization of pharmaceuticals to oxidative degradation.
Pharm Dev Technol
; 7(1): 1-32, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11852692
12.
Hydrolysis in pharmaceutical formulations.
Pharm Dev Technol
; 7(2): 113-46, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12066569